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MDMA (3,4-methylenedioxy-methamphetamine) is a synthetic, psychoactive drug that is similar to the stimulant amphetamine. Ecstasy also has similarities to the hallucinogen mescaline. MDMA is also referred to as ecstasy. More recently the drug is known as Molly. Ecstasy can be taken orally as a capsule or tablet. Molly (slang for “molecular”) refers to the pure crystalline powder form of MDMA. It is a capsule or powder when sold. MDMA is often abused in combination with other drugs.


The effects of ecstasy typically last between 3-6 hours. Unfortunately, this timeline is long enough to impair an individual at work. MDMA increases the activity of three neurotransmitters: serotonin, dopamine and norepinephrine. Therefore, taking the drug can cause feelings of increased energy, euphoria, emotional warmth, and empathy towards others.  Distortions in sensory and time perception are also common. Furthermore, extreme use can cause users to experience long-lasting confusion, depression, sleep abnormalities, and issues with attention and memory. Other physical effects include an increased heart rate, blood pressure, muscle tension, involuntary teeth clenching, nausea, blurred vision, faintness, chills or sweating. If taken in high doses it has the potential to hinder the ability to regulate body temperature. It can lead to an increase in body temperature. Rise in body temperature may result in damage to liver, kidney or cardiovascular systems failure, even death.

Users of MDMA can become a burden in the workplace and cost your company greatly.

AMC provides multiple drug screening panels for MDMA. The Department of Transportation (DOT) drug testing panel includes MDMA. AMC also offers a drug screen to mimic the DOT drug testing panel. A non-DOT NIDA Look-A-Like test mirrors the DOT panel. AMC offers drug screening programs for drug-free workplace as well as Department of Transportation programs.

National Institute on Drug Abuse; National Institutes of Health; U.S. Department of Health and Human Services